Using boronolectin in MALDI-MS imaging for the histological analysis of cancer tissue expressing the sialyl Lewis X antigen.
نویسندگان
چکیده
Certain carbohydrate-based biomarkers are known to correlate with cancer formation and progression. By targeting sialyl Lewis X, we have developed the first boronolectin-MS tag conjugate, which allows for MALDI-based imaging of cancer based on its cell surface carbohydrate.
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ورودعنوان ژورنال:
- Chemical communications
دوره 47 37 شماره
صفحات -
تاریخ انتشار 2011